Low-intensity ultrasound for drug-resistant temporal lobe seizures
Part of Brain & nervous system clinical trials.
This pilot study tests whether low-intensity focused ultrasound can reduce seizures in adults whose temporal lobe epilepsy hasn’t improved with at least two anti-seizure medicines. You may be asked to track seizure timing and undergo brain imaging before and during the study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 18 years old.
- Have drug-resistant temporal lobe epilepsy, with seizures that affect awareness, and have tried at least two anti-seizure medicines without enough control.
- Have about 1–2 seizures per month on average, and be able to track them reliably (you or a caregiver).
- Be able to understand and sign the consent form and cooperate with study testing.
- Be able to get a brain MRI (no implanted metal that makes MRI unsafe, and you can lie still for it).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a non-invasive focused ultrasound treatment for people with epilepsy that doesn't respond to medications. The goal is to see if this gentle ultrasound can reduce seizures without surgery.
This study tests a new device called NaviFUS that uses focused sound waves to gently stimulate a small area of the brain. It is for people whose seizures start in one part of the brain and are not fully controlled by seizure medicines.
This study tests if a new, non-invasive ultrasound treatment can safely reduce seizures in people whose seizures start in the temporal lobe and have not been controlled by at least two anti-epileptic drugs. The ultrasound is delivered through the scalp to gently stimulate the brain area where the seizures begin.
This trial tests a treatment called focused ultrasound, which uses sound waves to target and help control seizures in people whose epilepsy has not improved with at least two medications. It may offer a new option for those with localized epilepsy.
This trial tests a non-invasive procedure called magnetic resonance-guided focused ultrasound (MRgFUS) to treat epilepsy caused by brain lesions in children. This approach uses sound waves to target and destroy the lesion without surgery, which may reduce seizures.
This study tests a new, non-invasive treatment called 'temporal interference' for people whose epilepsy seizures are not controlled by medication. It aims to reduce seizures by using low-level electrical fields to calm overactive brain cells.
Hear when a new Drug Resistant Epilepsy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.