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NCT03886662Possibly a fitRecruiting

LB-100 for low-risk MDS after prior treatment failure

Myelodysplastic Syndromes

Treatments studied

Part of Blood & lymphatic clinical trials.

This Phase 1/2 trial studies LB-100 in adults with low or intermediate-1 risk myelodysplastic syndromes (MDS). It may help by improving blood counts or disease control in people whose prior treatments have not worked or stopped working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
47 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You can sign consent and follow study instructions.
  • You are 18 or older.
  • You have confirmed low or intermediate-1 risk MDS (or MDS/MPN) that needs treatment because of low blood counts.
  • Your kidneys and liver labs are adequate (kidney clearance ≥60, and liver enzymes below 3× the usual limit).
  • Your heart tests are acceptable and your performance status (energy/function) is 0–2.
  • If you had the non-5q or del(5q) form, you must have tried specific prior drugs and not responded or lost response.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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