High-flow oxygen for painful sickle cell episodes
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial tests whether giving high-flow oxygen can help treat a painful sickle cell “vaso-occlusive crisis” (VOC) and lower the risk of a serious lung complication. You may be eligible if you’re an adult with sickle cell disease experiencing an opioid-requiring pain flare and have higher risk for lung trouble.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have major sickle cell disease (SS, SC, or S-beta zero/plus types)
- You are having an acute pain episode (VOC) that needs opioid pain medicine
- You are at higher risk for a lung complication (based on blood counts and certain exam findings, or partly based on hydroxyurea use)
- You can give informed consent (and meet local social security/coverage rules)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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