Clin2
NCT04062721Possibly a fitNot yet recruiting

Immune system support after radiofrequency for liver tumors

Unresectable Colorectal Liver Metastases

Part of Cancer, Digestive system clinical trials.

This trial tests a treatment to boost the immune system after a procedure called radiofrequency ablation (RFA) that uses heat to destroy liver tumors. It is for people with colorectal cancer that has spread to the liver but not elsewhere, and aims to see if this can improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
12 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have colorectal cancer that has spread to the liver, but not to other parts of the body
  • You have at least 3 liver tumors that cannot be fully removed by surgery, but can be treated with RFA (a heat-based procedure)
  • Your liver function is good (checked with blood tests)
  • You have been on chemotherapy for at least 2 months and your disease is stable or responding
  • You have not had another cancer in the past 5 years (except for certain skin cancers or early-stage cervical cancer)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread

This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.

Aarhus
NCT06609434Not yet recruiting
Radiofrequency ablation for returning liver tumors from colorectal cancer

This trial is testing whether a procedure called radiofrequency ablation (using heat to destroy tumors) is safe and effective for people whose colorectal cancer has spread to the liver and come back there. It might help if you have a few small liver tumors that cannot be removed with surgery.

NCT06185556Recruiting· Phase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts

This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.

Amsterdam, North Holland
NCT06590259Recruiting· Phase 2
Ablation plus drug therapy for colorectal cancer liver metastases

This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.

Shanghai
NCT05492136Recruiting
Radiofrequency during liver surgery to reduce cancer coming back

This study looks at whether using radiofrequency (a heat-based treatment used during surgery) during liver surgery can lower the chances that cancer returns locally. It includes people with colorectal cancer that has spread to the liver and people with liver cancer (HCC).

Barcelona
NCT04150744Recruiting· Phase 2
New immune drug plus immunotherapy for liver cancer

This Phase 2 trial tests whether adding a new drug (RFA) to an immunotherapy medicine (carrizumab) works better than carrizumab alone for hepatocellular carcinoma, a type of liver cancer. It may help people whose tumors cannot be removed or transplanted and who have not started whole-body (systemic) cancer treatment yet.

Hangzhou, Zhejiang

Hear when a new Unresectable Colorectal Liver Metastases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.