Clin2
NCT04150497Possibly a fitRecruiting

Testing a new cell therapy for CD22-positive leukemia

B-cell Acute Lymphoblastic Leukemia

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This trial tests UCART22, a new cell-based treatment, for people with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) that has the CD22 marker. It may help by attacking leukemia cells that carry CD22.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
52 people
Ages
15 years to 50 years
Study type
Interventional

Who can take part

  • Your leukemia is B-ALL that has relapsed (came back) or is refractory (did not respond)
  • Your leukemia cells must test positive for CD22 (a marker on the cell surface)
  • You’ve already received standard chemotherapy, and you’ve also received a salvage treatment
  • You have not had any cell therapy or gene therapy in the last 90 days
  • You have not recently joined another investigational cell or gene therapy study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05674175Recruiting· Phase 1/Phase 2
Test two engineered immune cell treatments for B-cell leukemia

This trial tests a combination of two different engineered immune cell therapies to treat B-ALL (a leukemia). It’s designed for young people whose disease has come back, is hard to treat, or didn’t respond well to similar cell therapies.

Philadelphia, Pennsylvania
NCT07575971Recruiting· Phase 1/Phase 2
CAR-T Cell Therapy for High-Risk B-Cell Acute Lymphoblastic Leukemia

This trial tests a new type of immune cell therapy (CAR-T cells) designed to target leukemia cells after chemotherapy has put your disease into remission. The goal is to help prevent the leukemia from coming back, especially for patients at high risk of relapse.

Beijing, Beijing Municipality
NCT06559189Recruiting· Phase 1
A new CAR T therapy for children with relapsed B-ALL

This trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD22) found on leukemia cells. It is for children and young adults whose B-ALL has come back multiple times, or who have not responded to other treatments.

Aurora, Colorado
NCT06081478Recruiting· Phase 2
Targeted CAR-T cell therapy for advanced lymphoma or leukemia

This trial tests a new type of immune cell therapy (CAR-T) that targets two proteins on cancer cells—CD19 and CD22—to treat lymphoma or leukemia that has come back or not responded to standard treatment. It aims to see if this two-target approach works better.

Beijing, Beijing Municipality
NCT07575919Recruiting· Phase 1/Phase 2
CAR-T Cell Therapy for Standard-Risk B-ALL After Chemotherapy

This trial tests a new type of immunotherapy called CAR-T cells to help prevent relapse in adults with B-cell acute lymphoblastic leukemia (a blood cancer) who have responded well to standard chemotherapy. The treatment is designed as a consolidation therapy to strengthen remission after initial chemotherapy.

Beijing, Beijing Municipality
NCT07838714Recruiting· Phase 1
Cord blood CAR-T cells for relapsed B-cell leukemia

This trial tests a new type of personalized cell therapy using your own immune cells (called CAR-T cells) that are designed to find and attack leukemia cells that have certain markers (CD19 and CD22). It is for people whose leukemia has returned or not responded to standard treatments.

Shanghai, Shanghai Municipality

Hear when a new B-cell Acute Lymphoblastic Leukemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.