Study drug made from your immune cells for ALS
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests RAPA-501, a treatment made using your own immune cells, to slow progression of ALS. It may help by changing how your immune system responds in ALS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re an adult (age 18 or older), and you have ALS (sporadic or inherited).
- Your ALS symptoms started within the last 24 months.
- Your ALS function score (ALSFRS-R) is between 34 and 45.
- You must have enough immune cells for the treatment: CD3+ T-cells at least 500 cells per microliter from a blood test.
- You can still be on ALS medicines like riluzole, edaravone, or Relyvrio if your dose stayed the same for at least 30 days.
- Your breathing and blood tests must meet limits (breathing “slow vital capacity” at least 70%, and kidney/liver and bilirubin within set ranges).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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