Compare Gliadel implant versus focused brain radiation
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This Phase 2 study compares two ways to treat brain metastases: a Gliadel wafer placed during planned surgery versus focused stereotactic radiosurgery. It aims to see which approach works better and is safer for people with a limited number of brain tumor spots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (18+; in Nebraska, 19+).
- Your brain metastases are from a solid cancer, and you have up to 4 brain tumors (each up to 4 cm) with surgery planned for at least one spot.
- You have a planned Gliadel placement for only one surgical site.
- You must be well enough to undergo surgery (Karnofsky Performance Status above 60) and have a survival time of at least 3 months.
- Your blood test results for bleeding/clotting must be safe for surgery (INR 1.3 or less), and you must be able to have MRI scans.
- If you can become pregnant, you must have a negative pregnancy test within 7 days of starting.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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