De-escalating antibiotics early for neutropenic fever
Part of Blood & lymphatic clinical trials.
This study looks at whether doctors can safely use fewer/less intense antibiotics after fever improves in adults with low white blood cell counts after a stem cell transplant. It may help reduce unnecessary antibiotic exposure while still treating serious infections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and have had a hematopoietic stem cell transplant
- You currently have neutropenic fever: fever meeting specific temperature rules with very low neutrophils (ANC) or ANC expected to drop soon
- Your fever has gone away (temperature below 37.5°C) for at least 72 hours
- You can give informed consent to join the study
- You do NOT already have a confirmed bloodstream infection, skin/soft tissue infection, pneumonia, or a catheter-related infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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