Pre-surgery chemo plus robotic surgery for p16-positive throat cancer
Treatments studied
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This trial tests whether giving chemotherapy before robotic surgery works well for certain p16-positive oropharyngeal (throat) cancers. It aims to shrink or control the cancer and allow the surgeon to remove the tumor with clean margins while avoiding cancer spread beyond the neck.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have squamous cell cancer in the oropharynx (throat) that is p16 positive
- Your cancer is stage III or stage IVA (and not too advanced for surgery as defined by the trial)
- You have not had cancer treatment yet for this cancer (treatment naive)
- Cancer is not spread to distant organs (no distant metastasis)
- A surgeon believes the tumor can be removed through the mouth using a transoral robotic approach with clean margins
- Your blood counts and kidney function are strong enough for chemo (ANC over 2,000, platelets over 100,000, kidney clearance over 50)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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