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NCT04302870Possibly a fitRecruiting

Test medicines for motor neurone disease using adaptive trial design

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Treatments studied

Part of Brain & nervous system, Hormones & metabolism clinical trials.

This study tests treatments for motor neurone disease (MND) and assigns people to different treatment arms in an adaptive way. It may help doctors find out which medicine works best and for whom.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
1,150 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older and have a confirmed MND diagnosis (including ALS, primary lateral sclerosis, or progressive muscular atrophy)
  • If you can become pregnant (and fertile men), you must use effective contraception and follow the pregnancy-test rule
  • You are willing and able to follow the study plan and answer questionnaires
  • You must be able to give informed consent (with witness support if needed due to limb problems)
  • You do not have conditions that prevent safe participation (for example, certain severe mental health issues, active suicide thoughts, or pregnancy/breast-feeding)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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