Clin2
NCT04496349Possibly a fitRecruiting

Study of two medicines for relapsed T-PLL or NHL

T-Prolymphocytic LeukemiaNon-Hodgkins Lymphoma

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests APG-115 alone or with APG-2575 in adults whose T-PLL or NHL has come back or did not respond to treatment. It may help by targeting the cancer cells with a new drug approach when standard therapies have not worked.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
78 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You’re 18 years or older.
  • You have T-PLL that has returned or not responded, or you have a confirmed NHL that is relapsed, refractory, or can’t be treated with known helpful therapies.
  • You’ve had no chemotherapy or antibody therapy in the 7 days before starting study drugs (some fast-growing cases may use steroids or hydroxyurea until 24 hours before).
  • Blood counts and organ health must be adequate (neutrophils, hemoglobin, and platelets must meet minimums).
  • You’re well enough to function day-to-day (ECOG score 0–2).
  • You can understand the study and sign consent (or your legal representative can).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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