Clin2
NCT04517383Possibly a fitRecruiting

Sedation after clot-removal brain procedure: which helps recovery

Acute Ischemic StrokeEndovascular Thrombectomy

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial compares different types of calming medicine (sedation) after a procedure to remove a brain blood clot. It aims to see whether post-procedure sedation can improve recovery in people with a serious type of stroke.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,286 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are between 18 and 85 years old
  • You had an ischemic stroke where a large artery in the front of the brain is blocked (carotid or middle brain artery)
  • Before surgery, your stroke severity score (NIHSS) is 10 or higher
  • Before the stroke, you were mostly independent (modified Rankin scale mRS less than 3)
  • You already had clot removal under general anesthesia, and the procedure worked (mTICI 2b–3 confirmed by special X-ray imaging)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06139692Recruiting· Phase 4
Comparing light sedation during clot removal for stroke

This study compares two types of light sedation (medication to help you relax) during a procedure to remove a blood clot in the brain after a stroke. The goal is to find which sedation method helps patients recover better.

Nanjing, None Selected
NCT04916197Recruiting· Phase 4
Dexmedetomidine sedation after stroke clot removal

This Phase 4 study tests whether using a specific calming medicine (dexmedetomidine) for a longer period after a successful clot-removal procedure helps people do better in the long term. It may help improve outcomes after ischemic stroke where the clot is successfully treated.

Beijing, Beijing Municipality
NCT07115940Recruiting
Clot removal after 24 hours for stroke patients

This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.

Chicago, Illinois
NCT06663631Recruiting· Phase 1
Hibernation-like therapy for stroke recovery after clot removal

This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.

Linyi, Shandong
NCT07672795Not yet recruiting
Clot removal for severe back-of-brain stroke

This trial tests if a procedure to remove a blood clot from the main artery in the back of the brain (basilar artery) can help people who have a large stroke. The procedure is done within 24 hours of symptom onset, and researchers want to see if it can reduce disability.

NCT06143488Recruiting
Clot removal vs. best medicine for mild stroke with large vessel blockage

This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.

Wuhu, Anhui

Hear when a new Acute Ischemic Stroke trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.