Deferoxamine after aneurysm brain bleed to improve recovery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial studies deferoxamine, a medicine that targets iron-related injury, in people with an aneurysmal subarachnoid hemorrhage (a brain bleed caused by a burst aneurysm). It aims to improve neurologic recovery after the aneurysm is treated.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your brain bleed from an aneurysm (aneurysmal SAH) is confirmed by brain blood-vessel imaging
- Your aneurysm has already been treated with a procedure: endovascular (inside blood vessel) or microsurgery (open operation)
- You must be able to start the study medicine within 24 hours of symptom onset
- Your current brain condition is in a certain range of severity (Hunt-Hess 4 or less)
- Your baseline function before this bleed was independent (mRS 0–1) and you have consent from you or a legal representative
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares two medicines (deferoxamine and colchicine) to see if they can prevent further brain damage after a spontaneous brain bleed (intracerebral hemorrhage). The goal is to improve recovery by reducing inflammation and iron-related damage.
This study tests a combination of a minimally invasive surgery to remove the brain bleed and a medication called deferoxamine (which may help reduce damage from the bleed). The goal is to see if this combination helps improve recovery after a brain hemorrhage.
This trial uses brain MRI scans and memory/brain-function tests in people who are recovering from a specific type of brain bleed (aneurysmal subarachnoid hemorrhage). It aims to understand how the brain’s memory area changes after the event and how that may relate to memory function during rehabilitation.
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