Deferoxamine after aneurysm brain bleed to improve recovery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial studies deferoxamine, a medicine that targets iron-related injury, in people with an aneurysmal subarachnoid hemorrhage (a brain bleed caused by a burst aneurysm). It aims to improve neurologic recovery after the aneurysm is treated.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your brain bleed from an aneurysm (aneurysmal SAH) is confirmed by brain blood-vessel imaging
- Your aneurysm has already been treated with a procedure: endovascular (inside blood vessel) or microsurgery (open operation)
- You must be able to start the study medicine within 24 hours of symptom onset
- Your current brain condition is in a certain range of severity (Hunt-Hess 4 or less)
- Your baseline function before this bleed was independent (mRS 0–1) and you have consent from you or a legal representative
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares two medicines (deferoxamine and colchicine) to see if they can prevent further brain damage after a spontaneous brain bleed (intracerebral hemorrhage). The goal is to improve recovery by reducing inflammation and iron-related damage.
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