Study of two drugs for spontaneous brain bleed recovery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial compares two medicines (deferoxamine and colchicine) to see if they can prevent further brain damage after a spontaneous brain bleed (intracerebral hemorrhage). The goal is to improve recovery by reducing inflammation and iron-related damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have a spontaneous brain bleed (not from injury or an aneurysm) seen on a scan
- You arrived at the hospital within 24 hours of your first symptom
- You have moderate to severe stroke symptoms (NIHSS score higher than 8) and a Glasgow Coma Scale score of 8 or more
- You do not have chronic kidney disease or other serious illnesses that could interfere
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether the antibiotic minocycline can help people recover from a brain bleed (intracerebral hemorrhage). It is for adults who had a moderate to severe stroke, were independent before, and can start treatment within 24 hours.
This trial tests if the antibiotic minocycline can help people recover after a spontaneous brain bleed (intracerebral hemorrhage). It is for patients who have a moderate-sized bleed and are within 48 hours of symptoms starting.
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This study tests whether the drug tranexamic acid can help stop bleeding in the brain when given early. It is for people with a spontaneous brain bleed who are awake and can be treated within 6 hours.
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