Clin2
NCT04570085Possibly a fitRecruiting

Caffeine treatment to improve thinking in Alzheimer’s disease

Alzheimer Disease

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
248 people
Ages
50 years and older
Study type
Interventional

Who can take part

  • Be at least 50 years old
  • Have a confirmed “probable Alzheimer’s dementia” diagnosis with brain scan (CT/MRI) and routine blood tests
  • Have a thinking test score (MMSE) of 16 or higher
  • Have an informant/caregiver who lives with you during the study
  • Be able and willing to follow a low-caffeine diet (no regular tea, caffeinated soda, or large amounts of chocolate)
  • Not have untreated major depression or significant major anxiety based on clinician and questionnaire

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07230158Not yet recruiting
Brain stimulation for mild Alzheimer's (TRANSFORM-AD II)

This trial tests whether a gentle, non-invasive brain stimulation (transcranial alternating current) can improve memory and thinking in people with early Alzheimer's or mild memory problems. It involves regular sessions of stimulation and check-ups over several months.

Beijing, Beijing Municipality
NCT06619613Recruiting· Phase 1
Study of CM383 for early Alzheimer's disease

This trial tests a new drug called CM383 in people with mild cognitive impairment or mild Alzheimer's disease. The goal is to see if it can help slow down memory loss.

Hefei
NCT07543094Enrolling by invitation
Brain Stimulation for Early Alzheimer's Memory and Thinking

This study tests whether a special type of brain stimulation called temporal interference stimulation can improve memory and thinking skills in people with early-stage Alzheimer's disease. The treatment uses electrical stimulation to target specific brain areas without surgery.

Shanghai, Shanghai Municipality
NCT03810794Recruiting
Acupuncture study for people with Alzheimer’s memory problems

This trial tests whether acupuncture can improve symptoms in people with Alzheimer’s disease. You may qualify if you have memory and thinking changes consistent with Alzheimer’s and meet imaging and brain-scan score requirements.

Shanghai, Shanghai Municipality
NCT06756828Not yet recruiting
Melatonin for brain health in Alzheimer's

This study tests whether taking melatonin for 3 months can improve brain structure and blood markers in people with memory problems or early Alzheimer's. It involves brain scans and simple tests of thinking and physical function.

NCT07062198Recruiting· Phase 3
Metabolic supplement for Alzheimer's disease

This trial tests a special supplement combination designed to support brain energy use in people with Alzheimer's. It aims to see if the supplement can help slow cognitive decline.

Alanya

Hear when a new Alzheimer Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.