Nefopam for less pain after knee replacement surgery
Part of Brain & nervous system, Pain clinical trials.
This Phase 2 study tests whether oral nefopam can reduce pain after total knee replacement done with spinal anesthesia. It looks at whether this medicine works better than the usual post-surgery pain plan and how safely it can be used.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult (not a child) having a total knee replacement
- Your surgery plan includes spinal anesthesia (numbing medicine into the back)
- Your overall health is in the ASA 1 to 3 range (generally healthy to moderately healthy)
- You can sign a written consent form
- You have no conditions that make nefopam unsafe for you (including seizure history, urine retention/prostate issues, certain eye pressure problems, or certain heart rhythm/heart disease issues)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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