Clin2
NCT07485803Possibly a fitRecruiting

Methadone for pain after knee replacement

Total Knee Arthroplasty

Treatments studied

Part of Brain & nervous system clinical trials.

This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
192 people
Ages
21 years to 75 years
Study type
Interventional

Who can take part

  • You are between 21 and 75 years old.
  • You are having a total knee replacement on one knee (not both) at Colorado Joint Replacement.
  • You have not used narcotic pain medication in the past 6 weeks, and you have no history of drug or alcohol abuse.
  • You have not used tobacco in the last 90 days.
  • You do not have sleep apnea, severe kidney or liver disease, severe COPD, or a BMI over 40.
  • You are willing to use birth control (if you could become pregnant) and can stay in the hospital until you are able to go home (not to a rehab facility).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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