Nerve ablation for right-sided symptoms in HFpEF heart failure
Part of Heart & circulation clinical trials.
This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 40 or older.
- You have chronic HFpEF: heart failure symptoms needing water pills (diuretics) for over 30 days, and your heart failure has been at least moderate in the past year.
- You meet one of these “heart failure severity” checks: a recent heart-failure hospital stay, high NT-proBNP/BNP blood tests, or a right-heart pressure test showing high pressures.
- Your heart pumping strength is preserved: left-ventricular ejection fraction (LVEF) is at least 50% on an echo within the last 6 months.
- Your heart medicines have been stable for at least 30 days (with certain limits on big dose changes), and you have not started or stopped certain weight-loss medicines (GLP-1/GIP) around the study dates.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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