Nerve ablation for pulmonary hypertension from left heart disease
Part of Heart & circulation, Lungs & breathing clinical trials.
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have chronic heart failure due to left heart disease for at least 6 months, and you still have symptoms despite taking all recommended heart failure treatments.
- You have not been in the hospital for heart failure in the last month, and your medications have been stable for at least a month.
- Your resting blood pressure is between 90/60 and 160/100 mmHg, and your resting heart rate is between 50 and 100 beats per minute (or up to 110 if you have atrial fibrillation).
- You can walk between 100 and 450 meters in 6 minutes, and the limit is due to shortness of breath or fatigue, not other problems.
- You have a certain level of a heart stress marker (NT-proBNP) in your blood, which depends on your heart's pumping ability.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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