Clin2
NCT07403058Possibly a fitNot yet recruiting

Nerve treatment for heart failure with reduced pumping strength

Heart Failure With Reduced Ejection Fraction (HFrEF)

Part of Heart & circulation clinical trials.

This study tests a new procedure that uses heat to target a nerve near the kidneys. The goal is to reduce heart failure symptoms and improve heart function. It is for people with moderate heart failure who are already on standard medicines.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
40 years and older
Study type
Interventional

Who can take part

  • You have chronic heart failure, meaning you take a water pill (diuretic) and have symptoms like shortness of breath or fatigue.
  • You are at least 40 years old.
  • Your heart's pumping ability is between 20% and 40% (this is called ejection fraction).
  • You have been on a stable dose of heart failure medications for at least 30 days.
  • You have not had a heart attack, heart procedure, or hospitalization for heart failure in the last 30 days (or 3 months for some procedures).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04592445Recruiting
Nerve ablation for right-sided symptoms in HFpEF heart failure

This trial tests a procedure to “turn off” the right greater splanchnic nerve to improve symptoms in people with HFpEF (heart failure with preserved pumping function). If successful, it may reduce shortness of breath and fluid congestion in daily life.

Birmingham, Alabama
NCT07331220Not yet recruiting
Nerve treatment for heart failure with preserved ejection fraction

This trial tests a procedure called pulmonary artery denervation (using a catheter to treat nerves in the lung's blood vessels) for people with heart failure who still have a preserved ejection fraction (their heart squeezes normally but doesn't fill properly). The procedure aims to reduce pressure in the lungs and improve symptoms like shortness of breath. Participants must be on stable heart failure medications and have elevated BNP levels, among other requirements.

Nanjing, Jiangsu
NCT07558902Not yet recruiting
Kidney nerve treatment for heart failure

This trial tests a procedure that uses energy to calm overactive nerves in the kidney, which may help improve heart failure symptoms. It is for people with heart failure who are already on the best available medicines but still have symptoms.

Shanghai, Shanghai Municipality
NCT06733012Recruiting
Nerve block trial for heart failure patients

This trial tests a nerve block procedure to improve heart function in people with heart failure and reduced pumping ability. It aims to see if blocking certain nerves can help you feel better and be more active.

Durham, North Carolina
NCT06052072Enrolling by invitation
Heart failure trial testing nerve treatment for lung pressure

This trial tests a new treatment that uses a device to calm overactive nerves in the lung's blood vessels. It is for heart failure patients who also have high blood pressure in their lungs, to see if it can help them breathe easier and feel better.

Chicago, Illinois
NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease

This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.

Tucson, Arizona

Hear when a new Heart Failure With Reduced Ejection Fraction (HFrEF) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.