Clin2
NCT04686877Possibly a fitRecruiting

Surgery to remove deep brain bleeding with urokinase

Treatment of Spontaneous Intracerebral Hemorrhage

Part of Brain & nervous system clinical trials.

This trial tests whether a targeted (stereotactic) procedure to remove deep brain bleeding, combined with a medicine called urokinase, is safer and works better than standard care. It focuses on people whose bleeding is in the deep brain and who are able to undergo surgery within a specific time window.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
400 people
Ages
40 years and older
Study type
Interventional

Who can take part

  • You are age 40 or older
  • Your brain scan (CTA) was done 6 to 24 hours after symptoms started
  • The bleeding is from spontaneous (not caused by injury or known vessel problem) deep brain tissue, and the bleed is bigger than 25 mL
  • Your initial awareness level score (GCS) is between 9 and 15
  • You have some new movement weakness (motor deficit) and were fully independent before the bleed (mRS 0–1)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06868511Recruiting· Phase 3
Minimally invasive clot removal with tenecteplase for deep brain bleed

This trial tests a minimally invasive procedure to remove deep brain bleeds using a special puncture guided by brain imaging, combined with a clot-dissolving drug called tenecteplase. It may help reduce damage from the bleed and improve recovery.

Beijing, China
NCT07234955Recruiting
Minimally invasive surgery for deep brain bleeding

This trial tests a minimally invasive surgery to remove blood clots deep in the brain after a spontaneous bleed. It may help patients with moderate to large bleeds who are at least 18 and up to 80 years old.

Ho Chi Minh City, Ho Chi Minh
NCT05891509Recruiting
DTI-guided minimally invasive surgery for deep brain bleeding

This trial studies whether a special scan-guided, minimally invasive procedure can safely remove bleeding in the basal ganglia (deep in the brain) soon after it happens. It may help patients recover better by targeting the bleeding while protecting important brain pathways.

Ganzhou, Jiangxi
NCT04434807Recruiting
Surgery soon after brain bleed vs standard care

This trial tests whether removing a certain type of brain bleed (intracerebral hemorrhage) very early, using a minimally invasive surgery approach, improves outcomes compared with standard treatment. It may help people whose bleed is large enough and who can have surgery within a strict time window.

Newcastle, New South Wales
NCT05460793Recruiting
Surgery timing trial for brain bleeding after a stroke

This trial looks at whether starting brain surgery within 8 hours after a type of stroke called intracerebral hemorrhage (bleeding in the brain) can improve outcomes. It’s for adults with a certain amount and location of bleeding and without common causes like an aneurysm or malformation.

Amsterdam
NCT06465719Recruiting
Robot-assisted surgery for moderate brain bleeding

This trial tests if a minimally invasive surgery guided by a robotic AI system can help people with moderate bleeding deep inside the brain (basal ganglia). If you qualify, the surgery would happen within 72 hours of your stroke.

Hangzhou, Zhejiang

Hear when a new Treatment of Spontaneous Intracerebral Hemorrhage trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.