NAD+ for heart injury prevention around non-emergency surgery
Part of Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and able to sign consent before any study steps
- You are scheduled for a non-emergency heart surgery that uses a heart-lung machine (CPB)
- Your surgery plan must involve certain procedures (like CABG or valve repair/replacement)
- You have one or more risk factors, such as heart failure history, low LVEF, kidney function/eGFR <45, anemia, diabetes, or age 65+
- Your kidneys must not have had an acute injury in the 7 days before surgery (based on specific blood test criteria)
- You must not be pregnant, have kidney transplant or ESRD, be having off-pump or emergency surgery, or be enrolled in another competing study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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