Nasal oxytocin trial for people with hormone deficiency
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Kidney & urinary, Mental health, Women’s health & pregnancy clinical trials.
This early-phase study tests whether a spray of oxytocin in the nose can be given safely and may affect symptoms in people with arginine-vasopressin deficiency. You might qualify if your hormone levels are stable and you can safely take the nasal study medicine during the study period.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have arginine-vasopressin deficiency (a specific hormone/body-fluid condition).
- Your thyroid blood tests (FT4 or T4) and your blood sodium level are normal.
- You are on stable hormone replacement (no dose changes in the last 4 weeks, and no planned changes during the study).
- You do not have major safety exclusions, like recent substance use disorder, certain serious mental health history, or serious heart/kidney/liver disease.
- You can safely use the nasal spray (no long-term blocked nostrils or other nose problems that would prevent the spray from working).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a nasal spray containing oxytocin (a natural hormone) can help reduce pain and speed up recovery after pituitary surgery. It may help patients who are having their first pituitary surgery and meet the health requirements listed below.
This study measures oxytocin (a natural hormone) levels in children who have pituitary gland problems. Researchers want to understand if children with certain pituitary conditions don't make enough oxytocin, which could help guide future treatments.
This study tests whether the hormone oxytocin can help adolescents with obesity lose weight. You may be asked to stay on your usual diet and routines during the 18-week study to see how well the treatment works.
This Phase 2 study tests whether oxytocin can help improve bone health in children and teens with autism spectrum disorder. It also checks safety by monitoring symptoms and doing blood tests and imaging.
This study tests whether a nasal spray containing oxytocin can improve sexual well-being in people with a condition called arginine vasopressin deficiency (a problem with a hormone that controls water balance). Healthy volunteers who have mild sexual issues will also take part for comparison. Participants receive either the oxytocin spray or a placebo and fill out questionnaires about their sex life.
This study tests if a nasal spray with oxytocin (a natural hormone) can improve emotion recognition and reduce stress-related hormone levels in people with central diabetes insipidus compared to healthy volunteers.
Hear when a new Vasopressin Deficiency trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.