Clin2
NCT04848506Possibly a fitEnrolling by invitation

Long-term safety follow-up with aficamten for adults with HCM

Symptomatic Hypertrophic Cardiomyopathy (HCM)

Treatments studied

Part of Heart & circulation clinical trials.

This study checks how safe and well-tolerated aficamten is over the long run in adults with hypertrophic cardiomyopathy (HCM). You may be eligible if you finished a prior Cytokinetics aficamten study and your heart pumping strength is in the required range.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
900 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You completed a previous Cytokinetics trial that tested aficamten
  • Your heart pumping strength (LVEF) is at least 55% at the screening visit
  • You have not taken mavacamten within the last 56 days
  • You have not joined another research drug/device study within 1 month before screening
  • Since your prior aficamten study, you have not needed new atrial fibrillation treatment within 30 days
  • You have not had septal reduction treatment or a recent ICD placed

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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