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NCT04867317Possibly a fitRecruiting

Growth hormone treatment for veterans with mild traumatic brain injury and hormone deficiency

Adult Growth Hormone DeficiencyMild Traumatic Brain Injury

Part of Bones, joints & muscles, Brain & nervous system, Hormones & metabolism, Injuries & trauma clinical trials.

This study tests whether giving growth hormone, a natural substance that helps the body grow and repair tissues, can improve symptoms in veterans who have both a mild traumatic brain injury (concussion) and a deficiency in growth hormone. If you qualify, you may receive the treatment or a placebo (inactive shot), and the study will track your quality of life and symptoms over time.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
172 people
Ages
21 years to 55 years
Study type
Interventional

Who can take part

  • You are a veteran who served in Operations Enduring Freedom, Iraqi Freedom, or New Dawn (Afghanistan or Iraq wars).
  • You had at least one mild traumatic brain injury (concussion) during your military service, and it happened at least 12 months ago.
  • A blood test shows you have low growth hormone levels.
  • Your medications for mood, anxiety, or other mental health issues have been stable for at least 4 weeks, and other hormone treatments have been stable for 3 months.
  • You do not have a history of moderate or severe head injury, or other serious brain or mental health conditions (like bipolar disorder or schizophrenia).
  • You are not currently using certain medications or supplements (like growth hormone, estrogen, or high-dose steroids), and you are not pregnant or planning pregnancy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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