Immunotherapy for high-risk T-cell blood cancers after transplant
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This Phase 1 study tests a targeted immune treatment given after strong pre-treatment (myeloablative chemo plus total-body radiation) before or along with an allogeneic stem cell transplant. It may help prevent the cancer from coming back in young people with high-risk T-cell ALL or certain T-cell lymphomas.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be age 0 to 39 years.
- You have T-cell ALL in your second or later remission, or T-cell lymphoma that is in complete response after re-induction treatment.
- A stem cell transplant from a donor must be planned and the donor must be found.
- You need to be well enough to participate (performance status at least 60%) and have recovered from side effects of past treatments.
- You must meet standard blood, liver, kidney, and other organ function requirements.
- You (or your guardian) must be able to sign the study consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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