Prevention trial for stroke risk in people with high blood pressure
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 45 to 74 years
- Have primary high blood pressure (not “secondary” causes) and be on blood pressure medicine—or have high readings at two clinic visits
- Have MTHFR 677 TT genotype from a test done by a qualified lab
- Be able and willing to sign consent and follow study visits
- No stroke or major heart/circulation event during the study “run-in” period
- Not be on treatments or have illnesses that would rule you out (examples: prior stroke, dialysis, very poor kidney function, certain heart rhythm problems)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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