Folic acid plus strong blood-pressure treatment for hypertension
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether adding folic acid and using intensive blood-pressure lowering can improve brain blood-vessel damage in people with hypertension. It aims to reduce the worsening of small-vessel disease seen on brain scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 35 and 75 years old
- You have hypertension and your systolic blood pressure is in a target range (depending on how many BP medicines you take)
- Your brain scan shows specific small-vessel disease changes (for example, recent small stroke or certain white-matter changes)
- Your modified Fisher/Fazekas scan scores and history match the study’s pattern
- You have either high homocysteine (Hcy) (at least 10) or a specific MTHFR gene type (677 TT)
- Your functional status is good (mRS score 2 or less)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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