Clin2
NCT04982965Possibly a fitRecruiting

Study brain changes behind cannabis pain relief

SciaticaLumbar RadiculopathyLower Back PainDegenerative Disc DiseaseChronic Low-back Pain (cLBP)Chronic Low Back and Leg PainBack Pain

Part of Bones, joints & muscles, Brain & nervous system, Mental health, Pain clinical trials.

This early study looks at how the brain may respond to cannabis to reduce long-lasting lower back pain. You may be asked to follow strict rules about cannabis, opioids, and safety checks (including MRI) to help researchers understand the brain mechanisms.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
100 people
Ages
21 years to 65 years
Study type
Interventional

Who can take part

  • Be between 21 and 65 years old
  • Have had lower back pain for at least 3 months
  • Be off cannabis for at least 30 days, but have used THC in the past 2 years
  • Do not take opioids (and agree not to take opioids or barbiturates during the study)
  • If you could become pregnant: you must not be pregnant or breastfeeding
  • Be able to safely do study testing, including MRI (if required) and blood draws

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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