Alkali treatment to improve kidney graft blood vessel function
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether adding an “alkali” treatment (to raise low blood bicarbonate) can improve blood vessel and kidney graft function in people whose kidney transplant is about 1 year old. It may help if you have lower-than-normal bicarbonate levels while on stable transplant and blood pressure medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 80 and can give informed consent
- You had a kidney transplant about 1 year before starting the study
- Your blood bicarbonate is 16 to 24 on two blood tests at least 1 day apart
- Your kidney function is fairly preserved (eGFR at least 45)
- Your blood pressure is under 130/80 before randomization, and your medication plan is stable
- You are on a stable transplant medicine plan: tacrolimus, mycophenolate mofetil, and prednisone
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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