Targeted treatment versus standard care for older blood cancer patients
Part of Blood & lymphatic, Cancer clinical trials.
This Phase 2 trial compares a “precision” treatment plan with standard therapy for older adults with AML or MDS. It aims to improve outcomes while using treatments that may be better suited for people who cannot have intensive chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 60 or older, and have AML, related leukemia, or MDS
- Your leukemia is not acute promyelocytic leukemia, and you do not have the “favorable genetics” group that usually fits intensive chemotherapy
- You are not eligible for intensive chemotherapy or a stem cell transplant from another person
- Your body can handle treatment: kidney and liver function are adequate (or issues are mainly from the cancer), and heart condition is stable
- Your activity level is limited but not too low (performance status 0–2 if 75+; 0–3 if 60–74)
- You have enough time to benefit (life expectancy over 3 months) and you can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests a more precise type of whole bone-marrow radiation before a stem cell transplant. It may help patients with certain high-risk blood cancers by preparing the body for transplant more safely and effectively.
This trial compares two different combinations of chemotherapy drugs for older adults (ages 55-75) with newly diagnosed acute myeloid leukemia (AML) who are otherwise healthy enough to tolerate intensive treatment. The goal is to see which combination is more effective and has fewer side effects.
This early-phase trial tests whether a combination of targeted medicines can improve outcomes in people with higher-risk MDS or certain types of AML or CMML. It’s designed to find the safest dose and learn if the treatment can help the cancer respond.
This study matches people with acute myeloid leukemia (AML) to treatments based on their specific genetic markers. It aims to find the most effective therapy with fewer side effects compared to standard care.
This study looks at how “precision medicine” testing on your tumor (or planning to do it) can help guide possible targeted treatments for advanced cancer. It is observational, meaning researchers mainly watch and record what happens as testing results become available.
This trial tests a chemotherapy combination (Clad-LABU) to prepare older patients for a stem cell transplant. It is for people aged 50 or older with relapsed or refractory AML or high-risk MDS.
Hear when a new AML, Adult trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.