Atorvastatin for active moderate to severe Graves’ eye disease
Treatments studied
Part of Eyes & vision, Genetic & congenital, Hormones & metabolism, Immune system & allergy clinical trials.
This trial tests whether atorvastatin (a cholesterol-lowering pill) can improve active, moderate-to-severe Graves’ orbitopathy (eye swelling and bulging). It compares outcomes in people who meet specific safety and disease-activity requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Graves’ disease and your thyroid levels are controlled (euthyroid) on stable treatment
- Your eye condition is moderate-to-severe, with signs like eye bulging, double vision, or eyelid retraction
- Your Graves’ eye disease is active right now (your doctor measures an activity score of 3 or higher)
- You’re able to give written consent and attend regular follow-up visits
- Blood tests are safe: liver enzymes and CPK are no more than 3 times the normal upper limit
- You can meet pregnancy prevention rules if you can become pregnant, and avoid certain medicines before/during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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