Midodrine to reduce drip medicines in ICU patients
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether midodrine can help some ICU patients need less (or stop) a blood-pressure “drip” called vasopressors earlier. It’s meant to see if starting midodrine sooner can speed recovery and reduce how long you need these medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old
- You are currently receiving a vasopressor (a blood-pressure drip) in the ICU
- Your vasopressor dose is going down (being reduced)
- You can start treatment within 24 hours of your highest (peak) vasopressor dose
- You can take medicines by mouth or through a feeding tube (no reasons you can’t take “enteral” meds)
- You have not taken midodrine in the past 7 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if the oral medication midodrine can help wean patients with sepsis off IV vasopressors faster, potentially reducing ICU stays and complications.
This trial tests a pill called midodrine to see if it can safely raise blood pressure in people with heart failure and low blood pressure. It may help you feel better and avoid needing IV treatments while in the hospital.
This trial studies whether using blood-pressure support medicines (vasopressors) during breathing tube placement (intubation) can prevent dangerous drops in circulation (“cardiovascular collapse”). It may help patients stay stable during and after intubation, especially in critical illness.
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
This trial tests if a drug called vasopressin can help prevent acute kidney injury in patients at high risk. It's for adults in the ICU who have a predicted risk score of 5 or higher based on their lab and health data.
This study tests whether giving low-dose blood pressure medicines through a standard IV (instead of a larger central line) is safe and effective for patients with shock in the intensive care unit.
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