Collagen patch with stem cells for heart surgery patients
Part of Heart & circulation clinical trials.
This trial tests whether a special collagen patch containing stem cells can help people recover heart function after a heart attack. You would get the patch placed on your heart during bypass surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for heart bypass surgery within the next month.
- Your heart pumps less than 45% of its blood out (measured by a special MRI).
- You had a heart attack at least 3 months ago.
- At least 15% of your heart muscle is scarred (from the heart attack).
- You are not eligible for a heart transplant and do not have certain medical conditions like serious infections, recent stroke, or cancer that has not been cured.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a patch made from lab-grown heart muscle cells that is placed on the heart during bypass surgery. It aims to see if the patch can improve heart function in people with severe heart failure.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
This trial tests a new treatment using heart muscle cells made from stem cells (iPSC-CMs) combined with either a heart pump (LVAD) or bypass surgery (CABG) for people with end-stage heart failure. The goal is to see if adding these cells can help the heart work better.
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
This trial tests whether injecting special cells (HiCM-188) during bypass surgery can help improve heart function in people with advanced heart failure. The cells may help repair damaged heart tissue and improve your heart's ability to pump blood.
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