Heart patch with stem cells for damaged heart muscle
Part of Heart & circulation clinical trials.
This trial tests whether placing a special membrane with stem cells on the heart during bypass surgery can help improve heart function in people with a weak heart after a previous heart attack.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a planned heart bypass surgery within the next month.
- Your heart's pumping function is reduced (measured as LVEF of 45% or less).
- You had a heart attack at least 3 months ago, and the scarred area is large (at least 15% of the left heart muscle).
- You do not have a pacemaker or implantable defibrillator, and you can undergo MRI scans of the heart (CMRI).
- You are not on immunosuppressive therapy and do not have active cancer, autoimmune disease, or recent stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a patch made from lab-grown heart cells that is placed on the heart during bypass surgery. It aims to improve heart function in people with very advanced heart failure who are already having bypass surgery.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
This trial tests whether injecting special heart muscle cells (made from stem cells) during a heart bypass or a heart pump surgery can help improve your heart's function. It is for people with severe heart failure who are already planning one of these surgeries.
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
This trial tests whether injecting lab-grown heart cells into the heart can help people with heart failure whose heart pumps less than 40% of normal. It may help improve heart function and reduce symptoms.
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