Surgery-like brain radiation for up to 5 metastases
Part of Brain & nervous system, Cancer clinical trials.
This trial compares two ways of giving focused radiation to the brain for people with a limited number of brain metastases. It aims to see which schedule works best (and is likely best for costs and quality of life).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older
- Your overall health (performance status) must be 0 or 1, meaning you’re able to do most daily activities
- You have up to 5 brain metastases from certain cancers (kidney cancer, sarcoma, melanoma, or some lung, breast, or GI cancers), confirmed by biopsy or surgery
- The largest brain spots must be within about 10–25 mm, and the total treatment size must be limited (max cumulative volume 30 cm3)
- You need normal blood counts and cannot have certain high-risk brain findings like bleeding metastases or cancer spread to the brain lining
- You must be able to do brain MRI scans with contrast, use a mask during treatment, and agree to birth control if you can get pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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