Metformin study for children with Fragile X syndrome
Treatments studied
Part of Brain & nervous system, Genetic & congenital clinical trials.
This trial tests whether metformin is safe and helpful for children who have Fragile X syndrome. You may be considered if your child meets the health and medication rules and can attend regular follow-up visits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child has genetic test proof of Fragile X syndrome
- A parent/guardian can say “yes” to joining after being told the details
- Your child’s body weight is above the 3rd percentile for their age (not underweight)
- Your child is taking no more than 2 prescribed treatments/medicines at the moment
- Your child can come for regular check-ins and follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests an investigational medicine called MRM-3379 in males with Fragile X syndrome. It looks at how the medicine affects thinking and behavior over time.
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
This study tests whether a daily dose of CBD (a cannabis compound) can change brain activity in people with Fragile X syndrome. It also includes a healthy control group to compare results.
This trial tests if cannabidiol (CBD) can help with anxiety and improve brain function in people with Fragile X syndrome. Participants will receive CBD or a placebo, and may have brain scans (MRI) or magnetic stimulation (TMS) to see how it works.
This Phase 3 trial tests whether metformin can improve symptoms and safety in adults with genetically confirmed myotonic dystrophy type 1 (DM1). It may help reduce muscle problems, but you must meet specific walking, breathing, heart, and kidney requirements.
This trial tests an experimental medicine called SPG601 to see if it can help with Fragile X syndrome symptoms in adult males. It also checks how safe the medicine is.
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