Study of people at risk for inherited CJD before symptoms
Part of Brain & nervous system, Infections, Mental health clinical trials.
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a first-degree relative (parent, child, or sibling) of someone with E200K genetic CJD
- You are age 50 or older
- You agree to have genetic testing
- You do not currently have a diagnosis of CJD
- You can safely complete study visits and procedures, which may include MRI (brain scan) and a spinal fluid (LP) test
- You are not taking blood thinners that could make a spinal fluid test unsafe, and you do not have MRI or LP safety issues
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects information from patients diagnosed with Creutzfeldt-Jakob Disease (CJD), a rare brain condition, to better understand how it develops and progresses. Researchers will review your medical records, blood tests, brain scans, and other clinical data to identify patterns that could help future patients.
This study looks for early signs of prion disease in people who are at risk, using blood tests, spinal fluid, and thinking tests. It hopes to find ways to diagnose and track the disease earlier.
This study uses video calls to check on people with Creutzfeldt-Jakob disease (a rare brain disorder) and their care partners. It aims to understand how the disease progresses and improve support.
This trial tests an experimental medicine called ALN-6457 for adults with prion disease, a rare brain condition. The study aims to see if the drug is safe and if it can slow the disease.
This trial tests whether the drug efavirenz can help people with Creutzfeldt-Jakob disease (a rare brain disorder). The study aims to see if it can slow the disease and improve daily function.
This study follows people with a confirmed genetic nerve or brain disease over time, collecting blood and sometimes spinal fluid samples to learn more about the condition. It may help researchers understand how the disease progresses.
Hear when a new Creutzfeldt-Jakob Disease (CJD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.