Study of people at risk for inherited CJD before symptoms
Part of Brain & nervous system, Infections, Mental health clinical trials.
This study follows people who have a close family member with inherited Creutzfeldt-Jakob disease (CJD) to understand how the disease develops before any symptoms. It may involve genetic testing and safety-required procedures like brain scans and a spinal fluid test to learn about early changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a first-degree relative (parent, child, or sibling) of someone with E200K genetic CJD
- You are age 50 or older
- You agree to have genetic testing
- You do not currently have a diagnosis of CJD
- You can safely complete study visits and procedures, which may include MRI (brain scan) and a spinal fluid (LP) test
- You are not taking blood thinners that could make a spinal fluid test unsafe, and you do not have MRI or LP safety issues
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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