Study of ALN-6457 for adults with prion disease
Part of Brain & nervous system, Genetic & congenital, Hormones & metabolism, Infections, Mental health clinical trials.
This trial tests an experimental medicine called ALN-6457 for adults with prion disease, a rare brain condition. The study aims to see if the drug is safe and if it can slow the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of sporadic or genetic prion disease.
- You have a body mass index (BMI) below 35 at the screening visit.
- You are able to understand and complete questionnaires about your health.
- You do not have other serious medical conditions that could affect the trial.
- You have no history of brain or spinal disease that would interfere with a lumbar puncture (spinal tap).
- You have no allergies to local anesthetics (numbing medicine).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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