Clin2
NCT05168163Possibly a fitRecruiting

Atezolizumab plus targeted drug for advanced liver cancer

Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8Stage IVA Hepatocellular Carcinoma AJCC v8Stage IVB Hepatocellular Carcinoma AJCC v8

Treatments studied

Part of Cancer, Digestive system clinical trials.

This Phase 2 study tests whether atezolizumab combined with a multi-targeted (“multi-kinase”) inhibitor can treat advanced liver cancer that cannot be cured with surgery or local procedures. It focuses on people whose cancer has already grown despite a first-line treatment using atezolizumab plus bevacizumab.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
122 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be 18 years or older
  • Have liver cancer (hepatocellular carcinoma) confirmed by tests, and it must be advanced and not curable
  • Have already tried atezolizumab plus bevacizumab as first treatment and your cancer grew after that (second-line patients only)
  • Be able to return to the study clinic for follow-up during active treatment
  • Have good enough blood counts and liver function (reviewed by recent blood tests)
  • Have certain hepatitis virus test results (hepatitis B and C screening) and meet the study’s rules for active hepatitis

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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