Penpulimab plus cetuximab for advanced head and neck cancer
Part of Cancer clinical trials.
This trial studies penpulimab (an immune medicine) combined with cetuximab (an antibody drug) for recurrent or metastatic squamous cell head and neck cancer that cannot be treated with surgery or radiation. It aims to shrink tumors and improve survival in people whose tumor shows a specific immune marker (PD-L1).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older, and you have squamous cell cancer in the mouth, throat, voice box, or lower throat area
- Your cancer has come back or spread, and doctors don’t think surgery or radiation can control it
- You have at least one measurable tumor spot on scans
- Your tumor must be PD-L1 positive with CPS 1 or higher
- You need to be well enough to do treatment (ECOG performance status 0–1) and expect to live at least 3 months
- Your blood, liver, kidney, and clotting tests must meet safety limits, and you can’t have had blood transfusions within 14 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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