Clin2
NCT05323201Possibly a fitRecruiting

B7H3 CAR-T therapy for advanced liver cancer

Hepatocellular Carcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests an immune therapy made from your own blood cells (CAR-T) to treat advanced, unresectable liver cancer. It’s designed for people whose tumor has a specific marker called B7H3 and who meet blood, organ, and safety requirements.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
15 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • Be between 18 and 70 years old.
  • Have advanced liver cancer that cannot be removed with surgery, and it has spread or come back.
  • Your tumor must test positive for B7H3 (a specific cancer marker), from a biopsy or sample.
  • Your overall health should be fairly functional (ECOG score 0–2) and you should be expected to live at least 12 weeks.
  • Have blood counts and key organ function that meet study limits (for example, hemoglobin, platelets, white blood cells, and liver/kidney tests).
  • Be able to donate your own immune cells for making CAR-T (autologous blood cell collection), and sign informed consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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