Clin2
NCT05329285Possibly a fitRecruiting

Compare bypass or stent for heart weakness from blocked arteries

Coronary Artery Disease

Part of Heart & circulation clinical trials.

This study compares two ways to improve blood flow in people with weakened heart pumping (ischemic cardiomyopathy): bypass surgery (CABG) versus stent treatment (PCI). It aims to see which approach works better when the heart still has enough at-risk muscle and when best medical therapy is already started.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
470 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have ongoing heart failure symptoms despite treatment (NYHA class II–IV) within the last month.
  • Your heart’s pumping strength is low (LVEF 40% or less) from an accepted scan or test.
  • Your coronary angiogram shows a meaningful amount of heart muscle is in danger, and doctors think you can be fully revascularized with either stent or bypass.
  • You have started guideline-based heart medications for at least 1 month (or these are started in the hospital before randomization when possible).
  • You can sign the consent form and have no major reasons listed that would prevent taking both treatments safely.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05761067Recruiting
Trial for advanced heart weakness with low pumping ability

This study looks at treatment options for adults with significantly reduced heart pumping strength and extensive coronary artery disease. It may help people who are at higher risk due to widespread blocked heart arteries, but eligibility depends on recent heart events and bleeding risk.

Gothenburg
NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients

This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.

Los Angeles, California
NCT07269366Recruiting
Surgery vs stents for heart disease with weak heart pump

This trial compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stents (PCI)—in people whose heart pumps weakly (LVEF 40% or less). It aims to find which method works better for chest pain or recent heart issues.

Groningen
NCT06399692Recruiting· Phase 3
Choosing heart bypass or stents for women with heart disease

This study compares two common procedures to improve blood flow to the heart in women with blockages in multiple heart arteries. It aims to find which approach works better for women and may help guide future treatment decisions.

Glendale, California
NCT07349979Not yet recruiting
Heart artery opening plus medicines vs medicines alone for weak heart

This study compares two approaches for people with heart failure and a weak heart pump: opening blocked heart arteries with a stent plus standard medicines, versus standard medicines alone. It aims to see if adding the stent procedure improves outcomes.

Nanjing, Jiangsu
NCT06399705Recruiting· Phase 3
Comparing bypass surgery versus stenting for Black and Hispanic patients with coronary artery disease

This study compares two common ways to treat blocked heart arteries: bypass surgery and stenting. It aims to find which works better for Black and Hispanic patients with multiple blockages.

Glendale, California

Hear when a new Coronary artery disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.