Care plan for sickle cell pain crises in the ER
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This trial studies an approach to improve care during emergency room visits for uncomplicated sickle cell pain crises. It may help by guiding how pain is treated in the ER and tracking outcomes for people with sickle cell disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have sickle cell disease (not sickle cell trait).
- You are coming to the emergency department for an uncomplicated pain crisis.
- You received at least one opioid for pain in the emergency department.
- You do NOT have acute chest syndrome during this ER visit.
- You do NOT have a fever higher than 38.5°C (or 101.3°F) in the ER.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how children with sickle cell disease experience and manage pain crises, known as vaso-occlusive crises. The goal is to better understand these events to improve care for children living with this condition.
This trial tests if a non-steroidal anti-inflammatory drug (parecoxib) works as well as morphine for treating sickle cell pain crises in the emergency room. The goal is to find a safer pain relief option for people with sickle cell disease.
This study tests if using a bedside ultrasound (a quick, painless scan) of the chest and lungs can help doctors better understand and manage pain crises in people with sickle cell disease. If you are in the hospital for a severe pain crisis, you may be able to join.
This trial tests if adding lidocaine to standard pain treatment can reduce the amount of morphine or oxycodone needed for a severe pain crisis or acute chest syndrome in sickle cell disease. It is for adults in the ICU who have already started opioid treatment within the last 72 hours.
This trial tests if a low dose of ketamine can help relieve pain for people with sickle cell disease who come to the emergency room with a pain crisis. It aims to find a better way to manage pain during these episodes.
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
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