Clin2
NCT05397405Possibly a fitRecruiting

Improving cholesterol control after narrowing in brain arteries

Intracranial Artery Stenosis

Treatments studied

Part of Brain & nervous system, Heart & circulation clinical trials.

This study looks at strategies to improve cholesterol treatment in adults whose brain arteries are narrowed and who have had symptoms. Better cholesterol management may help reduce future problems related to this condition.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
180 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have moderate to severe narrowing in brain arteries that has caused symptoms, and you did not have procedures like clot-busting medicine, thrombectomy, or stenting inside the blood vessel.
  • Your LDL (“bad cholesterol”) is higher than 70 mg/dL (1.8 mmol/L).
  • You are able and willing to have MRI brain scans (often 3T) so the blood vessels can be measured for the study.
  • A clinician has told you that a statin (cholesterol-lowering medicine) is recommended for you.
  • You can sign the study consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06902740Recruiting· Phase 4
PCSK9 inhibitor with statin for asymptomatic brain artery narrowing

This trial tests whether adding a PCSK9 inhibitor to standard statin therapy can help people with narrowing in brain arteries that hasn't caused symptoms yet. The goal is to see if this combination lowers plaque and prevents future strokes.

Beijing, Beijing Municipality
NCT05692882Recruiting
Registry for stent treatment in narrowed brain arteries in China

This study records outcomes for people with significant narrowing in brain arteries who have treatment using a drug-eluting stent. It may help doctors understand how well this approach works and what risks or benefits to expect.

Chenzhou
NCT07605130Not yet recruiting· Phase 4
Brain training and cholesterol lowering for narrowed brain arteries

This study tests two approaches together: a computer-based brain training program and a stronger cholesterol-lowering medicine, to see if they can help improve memory and thinking in people with narrowed brain arteries. You would be randomly assigned to different combinations of the two, and the doctors will monitor your progress.

Beijing, Beijing Municipality
NCT07791823Not yet recruiting
Comparing two cholesterol-lowering treatments for narrowed brain arteries

This study tests two different strengths of cholesterol-lowering medicine (statins) to see which better prevents strokes in people with narrowed arteries inside the brain. It aims to find the safest and most effective level of treatment.

Seoul
NCT07036991Recruiting
Comparing two treatments for narrowed neck arteries

This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.

Shanghai
NCT07174375Not yet recruiting· Phase 2/Phase 3
Cholesterol-lowering drug after stroke treatment

This trial tests whether a cholesterol-lowering drug (called a PCSK9 inhibitor) can help people who had a stroke and a procedure to clear a blocked vessel. It aims to see if the drug reduces the risk of another stroke or improves recovery.

Fuzhou, Fujian

Hear when a new Intracranial Artery Stenosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.