Clin2
NCT07791823Possibly a fitNot yet recruiting

Comparing two cholesterol-lowering treatments for narrowed brain arteries

Intracranial Atherosclerosis ICAS

Part of Brain & nervous system, Heart & circulation clinical trials.

This study tests two different strengths of cholesterol-lowering medicine (statins) to see which better prevents strokes in people with narrowed arteries inside the brain. It aims to find the safest and most effective level of treatment.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,626 people
Ages
19 years to 80 years
Study type
Interventional

Who can take part

  • You are between 19 and 80 years old.
  • You have a narrowing of at least 50% in one of the major arteries inside your brain, confirmed by an imaging test in the past 12 months.
  • Your LDL ('bad') cholesterol is between 100 and 190 mg/dL, or you are already taking cholesterol-lowering medication.
  • You have at least one of these risk factors: high blood pressure, diabetes, current smoking, a family history of early heart disease, or chronic kidney disease.
  • You have never had a stroke or mini-stroke (TIA), and you have not had any prior brain artery stenting or surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06757764Recruiting· Phase 4
Stroke from artery narrowing: testing combination of anti-platelet drugs

This trial tests whether a combination of two or three anti-platelet medicines (like aspirin, clopidogrel, or cilostazol) is safe and works better than one alone for people who had a stroke from a narrowed artery. The goal is to prevent another stroke.

Seoul, Songpa-gu
NCT05974033Not yet recruiting
Stenting versus medication for narrowed brain arteries

This trial compares two treatments for people with a severely narrowed artery inside the brain that has recently caused a mini-stroke or stroke. One treatment uses a tiny mesh tube (stent) to open the artery; the other is medication alone. The goal is to see which approach better helps prevent future strokes.

NCT07605130Not yet recruiting· Phase 4
Brain training and cholesterol lowering for narrowed brain arteries

This study tests two approaches together: a computer-based brain training program and a stronger cholesterol-lowering medicine, to see if they can help improve memory and thinking in people with narrowed brain arteries. You would be randomly assigned to different combinations of the two, and the doctors will monitor your progress.

Beijing, Beijing Municipality
NCT05397405Recruiting
Improving cholesterol control after narrowing in brain arteries

This study looks at strategies to improve cholesterol treatment in adults whose brain arteries are narrowed and who have had symptoms. Better cholesterol management may help reduce future problems related to this condition.

Nanjing, Jiangsu
NCT07830277Not yet recruiting
Balloon treatment for narrowed brain arteries

This study compares using a special balloon to open narrowed brain arteries against just taking medicines. It aims to see which is better at preventing more strokes in people who have had symptoms from a severely narrowed artery.

Beijing, Beijing Municipality
NCT07309718Recruiting
Stroke Risk Assessment for Brain Artery Narrowing

This study looks at a new way to measure stroke risk in people with a specific type of brain artery narrowing (atherosclerosis) in the front part of the brain. You might participate if you have this condition and are willing to have imaging tests and take standard medicines.

Beijing, Xicheng District

Hear when a new Intracranial Atherosclerosis ICAS trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.