Gut microbiome study in young people with type 1 diabetes
Treatments studied
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This Phase 2 study looks at the gut microbiome (the bacteria in your intestines) in youth with type 1 diabetes, and how metformin may work differently through the gut. It may help researchers understand mechanisms and future treatment options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 11–18 years old and have type 1 diabetes at enrollment
- Have either a lean body size or be overweight/obese at enrollment
- You must not have a known single-gene (monogenic) cause of diabetes or type 2 diabetes
- Do not take antibiotics for infection within the past month
- Do not have immune problems or take immune-suppressing medicines (or regular steroids) in the past 6 months
- Do not have ongoing stomach/bowel illness in the past 6 months (including possible or confirmed celiac disease)
- Have not taken part in another research study with treatment in the past 3 months
- Do not have a history of using metformin (a type 2 diabetes medicine)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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