Comparing saline and albumin for fluid replacement in shock
Treatments studied
Part of Blood & lymphatic, Heart & circulation clinical trials.
This trial tests whether giving balanced salt solutions (like Ringer's) or albumin (a protein in blood) is better at helping patients in shock regain normal blood pressure and blood flow. It's a common treatment for shock, and this study aims to find which fluid works best.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must be in shock, meaning your body isn't getting enough blood flow, such as cold skin, low urine output, confusion, or high blood lactate (a sign of poor oxygen).
- Your doctor must confirm your body is likely to respond well to extra fluids (a 'fluid challenge' test).
- You must not be pregnant or breastfeeding.
- You must not be receiving ECMO or IABP (heart/lung support machines).
- You must not have had a recent heart attack or severe heart failure (NYHA class IV).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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