Metformin for fertility during thyroid cancer treatment
Treatments studied
Part of Cancer, Hormones & metabolism clinical trials.
This study tests whether the drug metformin, which is commonly used for diabetes, can help protect fertility in women who receive radioactive iodine (I-131) for thyroid cancer. If you join, you might take metformin during your treatment, and the researchers will monitor your fertility.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 18 and 44 years old
- You have papillary thyroid cancer (stage I or II)
- You have not yet had radioactive iodine treatment
- You do not have polycystic ovary syndrome (PCOS) or other ovarian problems
- You are not pregnant and not planning pregnancy during the study
- You have no major liver, kidney, or heart problems
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new radioactive treatment (177Lu-CTR-FAPI) that targets a protein on thyroid cancer cells. It's for people whose thyroid cancer has stopped responding to standard treatments, including radioactive iodine and targeted therapies.
This trial tests how much radiation a specialized whole-body PET/CT scan delivers in patients with differentiated thyroid cancer. It may help doctors better plan treatment for cancer that persists, returns, or has spread—especially when radioactive iodine (RAI) may or may not work.
This study looks at how different thyroid cancer treatments affect ovarian function and the ability to become pregnant in women aged 20-45. It aims to help women understand the impact of their treatment on future fertility.
This trial tests whether the common diabetes drug metformin helps improve the lining of the uterus (endometrium) in women with unexplained infertility, which could improve chances of getting pregnant. It might also help you because it is a simple pill with few side effects.
This trial tests whether adding metformin (a diabetes drug) to standard chemotherapy (FOLFIRI) and targeted therapy can help people with metastatic colorectal cancer live longer or respond better to treatment.
This study tests if metformin, a common diabetes medicine, can help reduce insulin resistance in women who finished chemotherapy for early-stage breast cancer. It aims to improve long-term health and prevent future problems.
Hear when a new Thyroid Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.