Clin2
NCT05504031Possibly a fitNot yet recruiting

Comparing hybrid heart treatment to bypass surgery for multi-vessel disease

Coronary Artery Disease

Part of Heart & circulation clinical trials.

This study compares two ways to treat blockages in multiple heart arteries: one is standard bypass surgery, the other combines a less invasive stent procedure with bypass surgery. The goal is to see which approach works better with fewer risks while fully restoring blood flow to your heart.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,048 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are 18 years or older and can give informed consent.
  • You have significant narrowing in at least two of your heart's major arteries (or their large branches), as confirmed by a heart specialist.
  • You have narrowing in the left anterior descending (LAD) artery and at least one other major artery of 2.5mm or more.
  • You do not have severe kidney disease (eGFR below 20).
  • You have not had a major heart attack (STEMI) within the last month and do not need emergency heart treatment.
  • You can take blood thinners (dual antiplatelet therapy) unless your doctor says it's unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07057713Not yet recruiting
Comparing two bypass surgery methods for multiple blocked arteries

This study compares two ways of doing bypass surgery for blocked heart arteries: using only chest and arm arteries versus a mix of arteries and leg veins. The goal is to see which approach works better for long-term heart health.

Changchun, Jilin
NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients

This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.

Los Angeles, California
NCT06399692Recruiting· Phase 3
Choosing heart bypass or stents for women with heart disease

This study compares two common procedures to improve blood flow to the heart in women with blockages in multiple heart arteries. It aims to find which approach works better for women and may help guide future treatment decisions.

Glendale, California
NCT05329285Recruiting
Compare bypass or stent for heart weakness from blocked arteries

This study compares two ways to improve blood flow in people with weakened heart pumping (ischemic cardiomyopathy): bypass surgery (CABG) versus stent treatment (PCI). It aims to see which approach works better when the heart still has enough at-risk muscle and when best medical therapy is already started.

Gothenburg
NCT06399705Recruiting· Phase 3
Comparing bypass surgery versus stenting for Black and Hispanic patients with coronary artery disease

This study compares two common ways to treat blocked heart arteries: bypass surgery and stenting. It aims to find which works better for Black and Hispanic patients with multiple blockages.

Glendale, California
NCT06378775Not yet recruiting
Robot-assisted heart bypass with stenting versus standard surgery

This trial compares a less invasive robot-assisted heart bypass plus stenting against standard heart bypass surgery. It is for people with multiple blocked heart arteries who have extra risk factors that make regular surgery more dangerous.

Hear when a new Coronary artery disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.