Clin2
NCT05505019Possibly a fitRecruiting

Using music to reduce apathy in Parkinson’s disease

Parkinson DiseaseApathy

Part of Brain & nervous system clinical trials.

This study tests whether music can help reduce apathy (low motivation) in people with Parkinson’s disease. It may help your mood and daily drive by targeting brain and behavior pathways tied to apathy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
40 years to 85 years
Study type
Interventional

Who can take part

  • You must have a confirmed Parkinson’s disease diagnosis based on standard criteria
  • You should not have “atypical Parkinsonism,” like PSP or multiple system atrophy
  • You must not have epilepsy
  • You must not have other major brain or nerve conditions, like stroke, MS, or a significant brain lesion
  • Your thinking (MoCA score) should be 21 or higher
  • Your depression level should not be moderate or severe

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05669170Not yet recruiting· Phase 2
Methylphenidate for apathy in Parkinson’s patients

This study tests whether methylphenidate can reduce apathy (lack of motivation) in people with Parkinson’s disease. It may help if apathy has been persistent for weeks and your Parkinson’s medicines have been stable.

NCT06087926Recruiting
TMS for apathy in Parkinson's disease

This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.

Chapel Hill, North Carolina
NCT07118956Recruiting
Ear stimulation for apathy in Parkinson's

This trial tests whether a gentle electrical stimulation on your ear (taVNS) can help improve low motivation (apathy) in people with Parkinson's. It also uses MRI scans to see how the treatment affects the brain.

Hefei, Anhui
NCT06991335Not yet recruiting
Deep brain stimulation for apathy in Parkinson's disease

This trial is testing whether a type of deep brain stimulation (called VC/VS-DBS) can help people with Parkinson's disease who have severe apathy (a loss of interest or motivation) that hasn't gotten better with medication. The goal is to see if this treatment can improve motivation and quality of life.

Houston, Texas
NCT04757220Recruiting
Study of apathy in people with schizophrenia or depression

This study looks at “apathy,” or reduced motivation/interest, in people with schizophrenia or depression. It may help researchers understand what drives apathy and how to measure it in a clearer, more complete way.

Strasbourg
NCT07461220Recruiting· Phase 1/Phase 2
Testing IRL757 for apathy in Parkinson's disease

This trial tests a new drug called IRL757 to see if it is safe and helps with apathy (loss of motivation or interest) in people with Parkinson's disease. You need to have at least moderate apathy and a caregiver who can come to visits with you.

Pleven

Hear when a new Apathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.